PROBLEM 3:

AGE-RELATED DECLINE IN IMMUNITY LEADS TO A DRAMATIC INCREASE IN THE INCIDENCE AND SEVERITY OF SHINGLES1,2

Increased Shingles Incidence With Age2

Bar graph showing the increased incidence of shingles with age
  • By age 85, the lifetime risk of shingles rises from 1:3 to 1:22,3
  • Postherpetic neuralgia (PHN) predominantly occurs in older patients. In a population-based study, 83% of shingles patients who developed PHN were ≥50 years old4

Not only does the risk of shingles increase with age, older persons are much more likely to experience postherpetic neuralgia, hospitalizations, and interference with activities of daily living.5

- Centers for Disease Control and Prevention, 2014

 

Increased Shingles Incidence With Age2

  • By age 85, the lifetime risk of shingles rises from approximately 1:3 to 1:22,3
  • Postherpetic neuralgia (PHN) predominantly occurs in older patients. In a population-based study, 83% of shingles patients who developed PHN were ≥50 years old4

Not only does the risk of shingles increase with age, older persons are much more likely to experience postherpetic neuralgia, hospitalizations, and interference with activities of daily living.5

—Centers for Disease Control and Prevention, 2014

 

References: 1. Kimberlin DW, Whitley RJ. Varicella–zoster vaccine for the prevention of herpes zoster. N Engl J Med. 2007;356(13):1338-1343. 2. Centers for Disease Control and Prevention. Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR. 2008;57(RR-5):1-30. 3. Schmader K. Herpes zoster in older adults. Clin Infect Dis. 2001;32(10):1481-1486. 4. Yawn BP, Saddier P, Wollan PC, St. Sauver JL, Kurland MJ, Sy LS. A population-based study of the incidence and complication rates of herpes zoster before zoster vaccine introduction. Mayo Clin Proc. 2007;82(11):1341-1349. 5. Centers for Disease Control and Prevention. Update on recommendations for use of herpes zoster vaccine. MMWR. 2014;63(33):729-731.

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